Influence of tPBM on resting-state electroencephalography. Box plot illustrates the median and range of power spectrum across all electrodes for each oscillatory frequency bands. (a) Effect of active tPBM on power spectrum pre (green line) and post (red line). (b) Effect of sham tPBM on power spectrum pre (green line) and post (red line). (c) Difference between Active and Sham tPBM: Change of power spectrum Post-Pre for active (red line) and sham (green line) tPBM. Active versus sham stimulation revealed significant lower alteration in delta and theta power and higher change in alpha, beta and gamma frequency bands.

 

Specifications

Manufacturer

Vielight Inc
LED Power

1000 mW per module
Power Density | Irradiance

100 mW/cm² (3) : Rear Transcranial LEDs
75 mW/cm² (1) : Frontal Transcranial LED
25 mW/cm² (1) : Intranasal LED
(Potential 300 mW/cm² but safety-limited)
Est. Irradiance Area

400cm² (+/- 50cm²) including Intranasal module footprint
Targeted Brain Network

Default Mode Network
Modules are adjustable to target different areas
Head Size Suitability

Minimum age: 5 years old based on published study data
Medical Grade Certification

ISO13485 and MDSAP
Safety Certification

TÜV Rheinland
Warranty

24 months

Downloads

Clinical Research

Condition | Topic Institution Vielight Device Research Type Status
  • Dementia

Published Study

 University of California San Francisco | US Veterans Affairs Vielight Neuro Gamma Clinical Study Completed
  • Dementia

Published Study

 Harvard Medical School | Boston University School of Medicine Vielight Neuro Gamma Clinical Study Completed
  • Alzheimer’s Disease

Clinical Trial Information

 Unity Health, Toronto Vielight Neuro Gamma Clinical Study Analysis Stage
  • Alzheimer’s Disease

Clinical Trial Information

 University of Florida | University of Arizona | National Institute on Aging Vielight 810 [MIP] Phase 2 Clinical Trial (n=168) Ongoing
  • Alzheimer’s Disease

Clinical Trial Information

 St Michael’s Hospital | Vielight Inc Vielight Neuro Gamma Phase 3 Clinical Trial
(n=228)		 Ongoing
  • Alzheimer’s Disease

Clinical Trial Information 

 University of California San Francisco | US Veterans Affairs Vielight Neuro Gamma Clinical Study Results Analysis
  • Traumatic Brain Injury (TBI)

Published Abstract 

Researchers and Participants Documentary

 Department of Neurology, University of Utah Vielight Neuro Gamma Clinical Trial (n=49) Pre-publication
  • Traumatic Brain Injury (CTE)

Published Study

 Boston University School of Medicine | Harvard Medical School Vielight Neuro Gamma Clinical Study Completed
  • Traumatic Brain Injury (TBI)

Published Study

 VA Advanced Imaging Research Center, San Francisco VA Health Care System Vielight Neuro Gamma Clinical Study Completed
  • Traumatic Brain Injury (TBI)

Clinical Trial Information 

 Boston Veterans Affairs Research Institute Vielight Neuro Gamma Clinical Study Ongoing
  • Parkinson’s Disease

Published Study

 University of Sydney Vielight Neuro Gamma Clinical Study Completed
  • Parkinson’s Disease

Clinical Trial Information

 University of Florida Vielight 810 [MIP] Phase 2 Clinical trial (n=135) Ongoing
  • Parkinson’s Disease

Clinical Trial Information 

 University of Sydney | University of Brisbane Vielight Neuro Gamma Clinical Study Registered
  • PTSD | Gulf War Illness

Published Study

 University of California San Francisco | US Veterans Affairs Vielight Neuro Alpha Clinical Study  Completed
  • Autism Spectrum Disorder (ASD)

Published Study

 Neurodevelopment Division, Istituto di Neuroscienze, Italy Vielight Neuro Duo Clinical Study  Completed
  • Covid-19 Recovery

Pre-print of Results

Medical Device License

 Vielight Inc Vielight RX Plus Pivotal Phase 3 Clinical Trial (n=295) Completed
  • Neuromodulation (Gamma 40Hz)

Published Study

 University of Toronto | Vielight Inc Vielight Neuro Gamma Clinical Study Completed
  • Neuromodulation (Alpha 10Hz)

Published Abstract

 Vielight Inc Vielight Neuro Alpha Clinical Study Pre- Publication
  • Microtubulin Photobiomodulation

Published Study

 Princeton University | University of Alberta | Vielight Inc Vielight Neuro Alpha Research Study Completed
  • COVID-19 Respiratory Symptoms

Pre-print of Results

Medical Device License

 Vielight Inc Vielight RX Plus Pivotal Phase 3 Clinical Trial (n=295) Completed
  • Antimicrobial Photodynamic Inactivation

Published Study Link

 Harvard Medical School Vielight Blue [MIP] Scientific Study  Completed
  • Antimicrobial Blue Light Therapy for Infectious Keratitis

Published Study Link

 Harvard Medical School Vielight Blue [MIP] Scientific Study  Completed
  • Antimicrobial blue light inactivation of Candida albicans

Published Study Link

 Harvard Medical School Vielight Blue [MIP] Scientific Study Completed
  • Enhancement of Divergent Creative Thinking

Published Study Link

 University of Deusto, Spain | University of Montpellier, France | Pennsylvania State University Vielight Neuro Gamma Clinical Research (n=56)  Completed
  • Spectroscopy Photobiomodulation and Tubulins: Implications for Alzheimer’s

Pre-print

 University of Alberta | Polytechnic University of Turin Vielight Neuro Alpha Scientific Study Completed
  • Alzheimer’s Disease (Dementia)

Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study  Device: Vielight Neuro Gamma ]


Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report
Co-authoring institutes – Harvard Medical School, Boston University School of Medicine

[ Published Study | Device: Vielight Neuro Gamma ]




Vielight Neuro RX Gamma – Alzheimer’s Disease Pivotal Phase III Clinical Trial (n=228)
Co-institutes – St Michael’s Hospital, Toronto

[ Clinical Trial Information Link ] (228 participants | 3 years | Ongoing)


Neuro RX Gamma for Amnestic Mild Cognitive Impairment (aMCI) / Dementia
Co-institutes – Unity Health Toronto, Toronto

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ]


Revitalizing Cognition in Older Adults at Risk for Alzheimer’s Disease With Near-Infrared Photobiomodulation

Institutes – University of Florida, University of Arizona, National Institute on Aging (NIA)

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (168 participants | 5 years | Registration)


Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer’s Disease
Institutes – University of California San Francisco UCSF

[ Clinical Trial Information Link / Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)


  • Traumatic Brain Injury / Concussion

Transcranial Photobiomodulation Treatment Effects In Former Athletes With Repetitive Head Hits (n=49)
Institutes – Department of Neurology, University of Utah

[ Published Abstract Link | Device: Vielight Neuro Gamma ] (49 participants | Pending publication)





Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy
Institutes – Boston University School of Medicine, Harvard Medical School

[ Published Study Link | Device: Vielight Neuro Gamma ]


Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case
Institutes – VA Advanced Imaging Research Center, San Francisco VA Health Care System, Departments of Radiology & Biomedical Imaging and Psychiatry & Behavioral Sciences, University of California, San Francisco

[ Published Study Link | Device: Vielight Neuro Gamma ]


Photobiomodulation to Improve Cognition in TBI, With fMRI
Institutes – Boston Veterans Affairs Research Institute

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (20 participants | 1 years | Ongoing)


  • Parkinson’s Disease

Improvements in clinical signs of Parkinson’s disease using photobiomodulation: A prospective proof-of-concept study
Institutes – University of Sydney, University of New South Wales, Griffith University

[ Published Study Link  Device: Vielight Neuro Gamma ]


Pilot Intervention With Near Infrared Stimulation
Institutes – University of Florida

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (135 participants | 4 years | Ongoing)


Evaluation of dose of Photobiomodulation (Light) Therapy and Physiotherapy for Improving Quality of Life Outcomes and Mobility in Parkinson’s Disease (Pilot)
Institutes – University of Sydney, University of Brisbane

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)

  • PTSD and Gulf War Illness

Improvements in Gulf War Illness Symptoms After Near-Infrared Transcranial and Intranasal Photobiomodulation: Two Case Reports
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study Link | Device: Vielight Neuro Alpha ]


  • Autism Spectrum Disorder (ASD)

Transcranial Photobiomodulation for the Treatment of Children with Autism Spectrum Disorder (ASD): A Retrospective Study
Institutes – Neurodevelopment Division, Istituto di Neuroscienze, Italy, Department of Psychiatry, Albert Einstein College of Medicine, NY

[ Published Study Link Device: Vielight Neuro Duo ]


  • Covid-19

Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms
Various clinical sites

[ Pre-print of Results ] (295 participants | 1 year | Pre-publication)

[ Medical Device License ]

  • Post-Covid

A Pilot Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment
Various clinical sites

[ Clinical Trial Information ] (36 participants | 1 year | Recruitment)


  • Cognitive Enhancement and EEG-Neuromodulation

Enhancement of Divergent Creative Thinking After Transcranial Near-Infrared Photobiomodulation Over the Default Mode Network
Institutes – University of Deusto | University of Montpellier | Pennsylvania State University

[ Published Study Link  Device: Vielight Neuro Gamma ]


Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study
Institutes – Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

[ Published Study Link (Nature, Scientific Reports, 2019) | Device: Vielight Neuro Gamma ]


Modulation of cortical oscillations using 10hz near-infrared transcranial and intranasal photobiomodulation: a randomized sham-controlled crossover study

[ Abstract Text Link | Device: Vielight Neuro Alpha ]


  • Bioenergetics and Cellular Enhancement

Near-Infrared Photobiomodulation of Living Cells, Tubulin, and Microtubules In Vitro
Institutes – Department of Physics and the Department of Chemistry, University of Alberta | Scholes Lab, Department of Chemistry, Princeton University, Princeton, NJ, United States | Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy | Vielight Inc

[ Published Study Link | Device: Vielight Neuro Alpha ]


Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer’s and Other Neurodegenerative Diseases
Institutes – University of Alberta, Polytechnic University of Turin, Freie Universit¨at Berlin, Silesian University of Technology

[ Pre-print | Device: Vielight Neuro Alpha ]


  • Systemic, Anti-Viral and Anti-Microbial

Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms
Various clinical sites

[ Pre-print of Results ] (295 participants | 1 year | Pre-publication)

[ Medical Device License ]


Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]


Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]


Antimicrobial blue light inactivation of Candida albicans: In vitro and in vivo studies
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]


FAQS

What wavelength does the Vielight Neuro emit?
The Vielight Neuro emits 810nm NIR energy.

Why the 810nm wavelength?
The 810nm wavelength has the deepest penetration through tissue and bone, enabling photonic diffusion to the brain.

What is the difference between the Duo, Gamma and Alpha models?
The Gamma model pulses NIR light energy at 40 Hz, which has a neuromodulating effect on Gamma neural oscillations. Theoretical benefits are increased memory activity, perception, cognition.

The Alpha model pulses NIR light energy at 10 Hz. This frequency is similar to neural alpha waves. Alpha waves are correlated with the brain’s resting state, offering support for mental coordination, mindfulness and learning.

The Duo makes both of these pulse rates available to you – having both pulse rates brings the most benefits.

How much power do your devices generate?
Our devices generate sufficient power to penetrate the skull and produce statistically significant results in independent research and clinical studies.

What is the recommended usage?
The general recommended usage is to use once every other day before experimenting with more frequent usage, not exceeding once per day. For more serious cognitive impairment, the recommendation is once per day, six days a week. Please note these recommendations are theoretical, anecdotal by nature and only based on published data or ongoing clinical trials with yet unpublished results.


What's included

Each device comes with:
1) 1 Neuro headset
2) 1 Neuro intranasal applicator
3) 1 Charger
4) 1 Device pouch
5) 1 Silicon sleeve
6) 1 Carry case

 

Videos