Vielight Neuro Duo 4 Vagus Combo

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Neuro Duo 4  Vagus Combo


Discover the Vielight Neuro-Vagus combo, a pioneering system that merges brain stimulation with vagus nerve stimulation to enhance brain function, systemic performance, and brain-body connectivity. Additionally, the world-exclusive Vielight Neuro Duo offers transcranial-intranasal photobiomodulation (PBM) for cognitive, memory, and blood flow improvements.

As the world’s only transcranial-intranasal brain photobiomodulation (PBM) device, the Vielight Neuro Duo is is the result of years of engineering and research.

Clinical research with our technology has produced improvements in cognitionmemory and blood flow.

The Vielight Neuro Duo comes with both Alpha and Gamma modes.

  • Gamma (40Hz): focus, memory, brain energy.
  • Alpha (10 Hz): relaxation and sleep improvement.

Vielight technology quality is guaranteed by medical grade certification.

Unlock Your Brain's Potential with the Vielight Neuro Duo

The Vielight Neuro Duo represents a powerful and extensively researched brain photobiomodulation (tPBM) device, featuring cutting-edge intranasal technology. It's designed to be safe, effective, and exceptionally user-friendly, offering the potential to unlock your brain's capabilities. Our patented transcranial-intranasal technology provides a unique and potent approach to stimulating the Default Mode Network in the brain.

The Neuro Duo emits pulsed near-infrared (NIR) energy through the cranium, initiating the process of photobiomodulation. Our engineering prowess allows us to extract one of the highest levels of power (~100 mW/cm2) from a near-infrared LED energy source, all while ensuring there is no heat generated.

This innovative device operates at two crucial frequencies:

  1. Gamma (40 Hz): Linked to enhanced focus, improved information processing, memory boost, and increased mental energy.
  2. Alpha (10 Hz): Supports mindfulness, facilitates learning, promotes relaxation, and can contribute to improved sleep.

Choose the Vielight Neuro Duo to embark on a journey of brain stimulation, where you can potentially experience amplified focus, cognitive performance, memory enhancement, relaxation, and better sleep. Our rigorous research and cutting-edge technology combine to offer you a powerful tool to tap into your brain's potential.

  • Vielight technology quality is guaranteed by medical grade certification.
  • Vielight technology is supported by a two-year manufacturer’s warranty from the time of delivery.

Why the nose?
Being just 3 inches from the brain, the intranasal channel is the most efficient channel for photobiomodulation of the ventral (underside) brain area. These ventral structures within the brain’s core have important functions.


Engineering behind the Vielight Neuro.

The Vielight Neuro enables direct contact with the scalp’s surface to maximize energy transmission and penetration while microchip-boosted cold LED diodes generate substantial power without releasing heat. Additionally, our patented intranasal technology enables photobiomodulation of the ventral brain areas.

Vielight Neuro – NIR light energy penetration.

Effects of the Vielight Neuro.

Default-mode network activity in
the PBM group—(A) baseline and (B) week
12 and in the usual care group—(C) baseline and (D) week 12. The posterior cingulate cortex (1, -61, and 38) was used as
seed in the analysis

Comparing EEG Power Spectrum:

Active vs Sham tPBM Using Non-Parametric Cluster-Based Permutation Test.

Non-parametric cluster-based permutation test comparing the rest EEG power spectrum between active and sham tPBM. Topographical maps are color-coded according to the permutation tests t-values. Clusters of electrodes with significant difference between the two conditions are marked in ‘+’ sign (p < 0.05 and αcluster = 0.01). (a) Difference between post and pre active tPBM. (b) Difference between post and pre sham tPBM. (c) Difference between pre active and sham tPMB. (d) Difference between post active and sham tPMB.

tPBM's Impact on Resting-State EEG:

Active vs Sham Stimulation Compared by Frequency Bands.

Influence of tPBM on resting-state electroencephalography. Box plot illustrates the median and range of power spectrum across all electrodes for each oscillatory frequency bands. (a) Effect of active tPBM on power spectrum pre (green line) and post (red line). (b) Effect of sham tPBM on power spectrum pre (green line) and post (red line). (c) Difference between Active and Sham tPBM: Change of power spectrum Post-Pre for active (red line) and sham (green line) tPBM. Active versus sham stimulation revealed significant lower alteration in delta and theta power and higher change in alpha, beta and gamma frequency bands.

Product Features:

- Optimal Stimulation: Uses NIR energy for effective brain and vagal nerve stimulation.

- Advanced Engineering:High irradiance with minimal heat production.

- Dual Modes: Alpha (10Hz) for relaxation and sleep; Gamma (40Hz) for focus, memory, and energy.

- Medical Grade: Quality guaranteed with medical certification.


Clinical Benefits: 

- Enhanced cognition and memory.

- Improved systemic performance and brain-body connection.

- Regulation of heart rate, digestion, immune responses, and mood.


Support and Quality Assurance
:


- Free Consultation: Available before and after purchase.

- Warranty:2-year manufacturer’s warranty for peace of mind.

- Shipping: Depots in the USA, with Delivery times range from 2-14 business days.

- Returns: 6-months, no-questions-asked return policy, offering 80% refund.


Important Note:To ensure customer satisfaction and support, warranty and returns only apply to purchases made through authorized channels—devices bought through unauthorized sellers like Amazon and eBay are excluded.

Vielight Vagus


The Vielight Vagus enables non-invasive vagus nerve stimulation (VNS) via photobiomodulation (PBM). This device was engineered to enhance brain-body connectivity via the vagus nerve.

The Vielight Vagus can be used together with the Vielight Neuro to complement and maximize outcomes.

Why the vagus nerve?

The vagus nerve is crucial in regulating many of our bodies’ most basic functions. One of the most important aspects of the vagus nerve is its direct connection between the brain and the gut.

Neuroplasticity: VNS has been associated with promoting changes in the brain’s structure and function, improving connectivity and neural network efficiency.

Cognitive Enhancement: Studies have explored the impact of VNS on cognitive functions. Some findings suggest improvements in memory, attention, and other cognitive domains.

Inflammation and Health: VNS has also been investigated for its potential effects on reducing inflammation and improving overall health outcomes.

Specifications

Neuro Duo 4

Manufacturer

Vielight Inc

LED Power

1000 mW per module

Power Density | Irradiance

100-150 mW/cm² (3) : Rear Transcranial LEDs
75-125 mW/cm² (1) : Frontal Transcranial LED
25-50 mW/cm² (1) : Intranasal LED
(Potential 300 mW/cm² but safety-limited)

Est. Irradiance Area

400cm² (+/- 50cm²) including Intranasal module footprint

Targeted Brain Network

Default Mode Network
Modules are adjustable to target different areas

Head Size Suitability

Minimum age: 5 years old based on published study data

Medical Grade Certification

ISO13485 and MDSAP

Safety Certification

TÜV Rheinland

Warranty

24 months

Satisfaction Guarantee

We have an 80% refund policy, valid for 6 months from the time of purchase


Vielight Vagus

Manufacturer

Vielight Inc

LED Power

500 mW per module

Power Density | Irradiance

50 mW/cm² (2) : Bilateral LEDs
25 mW/cm² (1) : Intranasal LED
(Potential 300 mW/cm² but safety-limited)

Est. Irradiance Area

400cm² (+/- 50cm²) including Intranasal module footprint

Medical Grade Certification

ISO13485 and MDSAP

Safety Certification

TÜV Rheinland

Warranty

24 months

Satisfaction Guarantee

We have an 80% refund policy, valid for 6 months from the time of purchase


This product includes an intranasal applicator for enhanced delivery and effectiveness.

 Videos 







Clinical Research

Condition | Topic Institution Vielight Device Research Type Status
  • Dementia

Published Study

University of California San Francisco | US Veterans Affairs Vielight Neuro Gamma Clinical Study Completed
  • Dementia

Published Study

Harvard Medical School | Boston University School of Medicine Vielight Neuro Gamma Clinical Study Completed
  • Alzheimer’s Disease

Clinical Trial Information

Unity Health, Toronto Vielight Neuro Gamma Clinical Study Analysis Stage
  • Alzheimer’s Disease

Clinical Trial Information

University of Florida | University of Arizona | National Institute on Aging Vielight 810 [MIP] Phase 2 Clinical Trial (n=168) Ongoing
  • Alzheimer’s Disease

Clinical Trial Information

St Michael’s Hospital | Vielight Inc Vielight Neuro Gamma Phase 3 Clinical Trial
(n=228)
Ongoing
  • Alzheimer’s Disease

Clinical Trial Information 

University of California San Francisco | US Veterans Affairs Vielight Neuro Gamma Clinical Study Results Analysis
  • Traumatic Brain Injury (TBI)

Published Abstract 

Researchers and Participants Documentary

Department of Neurology, University of Utah Vielight Neuro Gamma Clinical Trial (n=49) Pre-publication
  • Traumatic Brain Injury (CTE)

Published Study

Boston University School of Medicine | Harvard Medical School Vielight Neuro Gamma Clinical Study Completed
  • Traumatic Brain Injury (TBI)

Published Study

VA Advanced Imaging Research Center, San Francisco VA Health Care System Vielight Neuro Gamma Clinical Study Completed
  • Traumatic Brain Injury (TBI)

Clinical Trial Information 

Boston Veterans Affairs Research Institute Vielight Neuro Gamma Clinical Study Ongoing
  • Parkinson’s Disease

Published Study

University of Sydney Vielight Neuro Gamma Clinical Study Completed
  • Parkinson’s Disease

Clinical Trial Information

University of Florida Vielight 810 [MIP] Phase 2 Clinical trial (n=135) Ongoing
  • Parkinson’s Disease

Clinical Trial Information 

University of Sydney | University of Brisbane Vielight Neuro Gamma Clinical Study Registered
  • PTSD | Gulf War Illness

Published Study

University of California San Francisco | US Veterans Affairs Vielight Neuro Alpha Clinical Study  Completed
  • Autism Spectrum Disorder (ASD)

Published Study

Neurodevelopment Division, Istituto di Neuroscienze, Italy Vielight Neuro Duo Clinical Study  Completed
  • Covid-19 Recovery

Pre-print of Results

Medical Device License

Vielight Inc Vielight RX Plus Pivotal Phase 3 Clinical Trial (n=295) Completed
  • Neuromodulation (Gamma 40Hz)

Published Study

University of Toronto | Vielight Inc Vielight Neuro Gamma Clinical Study Completed
  • Neuromodulation (Alpha 10Hz)

Published Abstract

Vielight Inc Vielight Neuro Alpha Clinical Study Pre- Publication
  • Microtubulin Photobiomodulation

Published Study

Princeton University | University of Alberta | Vielight Inc Vielight Neuro Alpha Research Study Completed
  • COVID-19 Respiratory Symptoms

Pre-print of Results

Medical Device License

Vielight Inc Vielight RX Plus Pivotal Phase 3 Clinical Trial (n=295) Completed
  • Antimicrobial Photodynamic Inactivation

Published Study Link

Harvard Medical School Vielight Blue [MIP] Scientific Study  Completed
  • Antimicrobial Blue Light Therapy for Infectious Keratitis

Published Study Link

Harvard Medical School Vielight Blue [MIP] Scientific Study  Completed
  • Antimicrobial blue light inactivation of Candida albicans

Published Study Link

Harvard Medical School Vielight Blue [MIP] Scientific Study Completed
  • Enhancement of Divergent Creative Thinking

Published Study Link

University of Deusto, Spain | University of Montpellier, France | Pennsylvania State University Vielight Neuro Gamma Clinical Research (n=56)  Completed
  • Spectroscopy Photobiomodulation and Tubulins: Implications for Alzheimer’s

Pre-print

University of Alberta | Polytechnic University of Turin Vielight Neuro Alpha Scientific Study Completed
  • Alzheimer’s Disease (Dementia)

Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study  Device: Vielight Neuro Gamma ]


Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report
Co-authoring institutes – Harvard Medical School, Boston University School of Medicine

[ Published Study | Device: Vielight Neuro Gamma ]




Vielight Neuro RX Gamma – Alzheimer’s Disease Pivotal Phase III Clinical Trial (n=228)
Co-institutes – St Michael’s Hospital, Toronto

[ Clinical Trial Information Link ] (228 participants | 3 years | Ongoing)


Neuro RX Gamma for Amnestic Mild Cognitive Impairment (aMCI) / Dementia
Co-institutes – Unity Health Toronto, Toronto

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ]


Revitalizing Cognition in Older Adults at Risk for Alzheimer’s Disease With Near-Infrared Photobiomodulation

Institutes – University of Florida, University of Arizona, National Institute on Aging (NIA)

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (168 participants | 5 years | Registration)


Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer’s Disease
Institutes – University of California San Francisco UCSF

[ Clinical Trial Information Link / Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)


  • Traumatic Brain Injury / Concussion

Transcranial Photobiomodulation Treatment Effects In Former Athletes With Repetitive Head Hits (n=49)
Institutes – Department of Neurology, University of Utah

[ Published Abstract Link | Device: Vielight Neuro Gamma ] (49 participants | Pending publication)





Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy
Institutes – Boston University School of Medicine, Harvard Medical School

[ Published Study Link | Device: Vielight Neuro Gamma ]


Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case
Institutes – VA Advanced Imaging Research Center, San Francisco VA Health Care System, Departments of Radiology & Biomedical Imaging and Psychiatry & Behavioral Sciences, University of California, San Francisco

[ Published Study Link | Device: Vielight Neuro Gamma ]


Photobiomodulation to Improve Cognition in TBI, With fMRI
Institutes – Boston Veterans Affairs Research Institute

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (20 participants | 1 years | Ongoing)


  • Parkinson’s Disease

Improvements in clinical signs of Parkinson’s disease using photobiomodulation: A prospective proof-of-concept study
Institutes – University of Sydney, University of New South Wales, Griffith University

[ Published Study Link  Device: Vielight Neuro Gamma ]


Pilot Intervention With Near Infrared Stimulation
Institutes – University of Florida

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (135 participants | 4 years | Ongoing)


Evaluation of dose of Photobiomodulation (Light) Therapy and Physiotherapy for Improving Quality of Life Outcomes and Mobility in Parkinson’s Disease (Pilot)
Institutes – University of Sydney, University of Brisbane

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)


  • PTSD and Gulf War Illness

Improvements in Gulf War Illness Symptoms After Near-Infrared Transcranial and Intranasal Photobiomodulation: Two Case Reports
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study Link | Device: Vielight Neuro Alpha ]


  • Autism Spectrum Disorder (ASD)

Transcranial Photobiomodulation for the Treatment of Children with Autism Spectrum Disorder (ASD): A Retrospective Study
Institutes – Neurodevelopment Division, Istituto di Neuroscienze, Italy, Department of Psychiatry, Albert Einstein College of Medicine, NY

[ Published Study Link Device: Vielight Neuro Duo ]


  • Covid-19

Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms
Various clinical sites

[ Pre-print of Results ] (295 participants | 1 year | Pre-publication)

[ Medical Device License ]

  • Post-Covid

A Pilot Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment
Various clinical sites

[ Clinical Trial Information ] (36 participants | 1 year | Recruitment)


  • Cognitive Enhancement and EEG-Neuromodulation

Enhancement of Divergent Creative Thinking After Transcranial Near-Infrared Photobiomodulation Over the Default Mode Network
Institutes – University of Deusto | University of Montpellier | Pennsylvania State University

[ Published Study Link  Device: Vielight Neuro Gamma ]


Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study
Institutes – Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

[ Published Study Link (Nature, Scientific Reports, 2019) | Device: Vielight Neuro Gamma ]


Modulation of cortical oscillations using 10hz near-infrared transcranial and intranasal photobiomodulation: a randomized sham-controlled crossover study

[ Abstract Text Link | Device: Vielight Neuro Alpha ]


  • Bioenergetics and Cellular Enhancement

Near-Infrared Photobiomodulation of Living Cells, Tubulin, and Microtubules In Vitro
Institutes – Department of Physics and the Department of Chemistry, University of Alberta | Scholes Lab, Department of Chemistry, Princeton University, Princeton, NJ, United States | Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy | Vielight Inc

[ Published Study Link | Device: Vielight Neuro Alpha ]


Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer’s and Other Neurodegenerative Diseases
Institutes – University of Alberta, Polytechnic University of Turin, Freie Universit¨at Berlin, Silesian University of Technology

[ Pre-print | Device: Vielight Neuro Alpha ]


  • Systemic, Anti-Viral and Anti-Microbial

Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms
Various clinical sites

[ Pre-print of Results ] (295 participants | 1 year | Pre-publication)

[ Medical Device License ]


Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]


Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies
Institutes – Harvard Medical School

[ Published Study Link Vielight MIP ]


Antimicrobial blue light inactivation of Candida albicansIn vitro and in vivo studies
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]




Customer Reviews

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Anna Ignatenko
Was super late but has finally arrived (Originally Ordered 3/2/24)

I've been using the Duo combo, and in all honesty, I can tell it works, but the devices are not comfortable at all. The head portion doesn't fit comfortably and presses too much on the forehead, where there should most likely be a cushion. The vagus nerve one also doesn't sit properly and falls off, it's hard to keep it on the side of the neck the directions say to place it, as it just slides off. I have two very old models of the nostril 633 and 810 from vie light years ago that sit comfortably still to this day when used; the nostril pieces for both the duo and the vagus are too tight and squeeze the nostrils - I'm not sure why vie light did this, it's painful and uncomfortable.


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